20,546 research outputs found

    Multiple-Access Bosonic Communications

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    The maximum rates for reliably transmitting classical information over Bosonic multiple-access channels (MACs) are derived when the transmitters are restricted to coherent-state encodings. Inner and outer bounds for the ultimate capacity region of the Bosonic MAC are also presented. It is shown that the sum-rate upper bound is achievable with a coherent-state encoding and that the entire region is asymptotically achievable in the limit of large mean input photon numbers.Comment: 11 pages, 5 figures, corrected two figures, accepted for publication in Phys. Rev.

    Joint analysis of SNP and gene expression data in genetic association studies of complex diseases

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    Genetic association studies have been a popular approach for assessing the association between common Single Nucleotide Polymorphisms (SNPs) and complex diseases. However, other genomic data involved in the mechanism from SNPs to disease, for example, gene expressions, are usually neglected in these association studies. In this paper, we propose to exploit gene expression information to more powerfully test the association between SNPs and diseases by jointly modeling the relations among SNPs, gene expressions and diseases. We propose a variance component test for the total effect of SNPs and a gene expression on disease risk. We cast the test within the causal mediation analysis framework with the gene expression as a potential mediator. For eQTL SNPs, the use of gene expression information can enhance power to test for the total effect of a SNP-set, which is the combined direct and indirect effects of the SNPs mediated through the gene expression, on disease risk. We show that the test statistic under the null hypothesis follows a mixture of χ2\chi^2 distributions, which can be evaluated analytically or empirically using the resampling-based perturbation method. We construct tests for each of three disease models that are determined by SNPs only, SNPs and gene expression, or include also their interactions. As the true disease model is unknown in practice, we further propose an omnibus test to accommodate different underlying disease models. We evaluate the finite sample performance of the proposed methods using simulation studies, and show that our proposed test performs well and the omnibus test can almost reach the optimal power where the disease model is known and correctly specified. We apply our method to reanalyze the overall effect of the SNP-set and expression of the ORMDL3 gene on the risk of asthma.Comment: Published in at http://dx.doi.org/10.1214/13-AOAS690 the Annals of Applied Statistics (http://www.imstat.org/aoas/) by the Institute of Mathematical Statistics (http://www.imstat.org

    Definition, analysis and development of an optical data distribution network for integrated avionics and control systems. Part 2: Component development and system integration

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    Fiber optic transmission is emerging as an attractive concept in data distribution onboard civil aircraft. Development of an Optical Data Distribution Network for Integrated Avionics and Control Systems for commercial aircraft will provide a data distribution network that gives freedom from EMI-RFI and ground loop problems, eliminates crosstalk and short circuits, provides protection and immunity from lightning induced transients and give a large bandwidth data transmission capability. In addition there is a potential for significantly reducing the weight and increasing the reliability over conventional data distribution networks. Wavelength Division Multiplexing (WDM) is a candidate method for data communication between the various avionic subsystems. With WDM all systems could conceptually communicate with each other without time sharing and requiring complicated coding schemes for each computer and subsystem to recognize a message. However, the state of the art of optical technology limits the application of fiber optics in advanced integrated avionics and control systems. Therefore, it is necessary to address the architecture for a fiber optics data distribution system for integrated avionics and control systems as well as develop prototype components and systems

    Classical Extended Conformal Algebras Associated with Constrained KP Hierarchy

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    We examine the conformal property of the second Hamiltonian structure of constrained KP hierarchy derived by Oevel and Strampp. We find that it naturallygives a family of nonlocal extended conformal algebras. We give two examples of such algebras and find that they are similar to Bilal's V algebra. By taking a gauge transformation one can map the constrained KP hierarchy to Kuperschmidt's nonstandard Lax hierarchy. We consider the second Hamiltonian structure in this representation. We show that after mapping the Lax operator to a pure differential operator the second structure becomes the sum of the second and the third Gelfand-Dickey brackets defined by this differential operator. We show that this Hamiltonian structure defines the W-U(1)-Kac-Moody algebra by working out its conformally covariant form.Comment: NHCU-HEP-94-28, 19 pages (Plain TeX

    Flight Flutter Testing of Rotary Wing Aircraft Using a Control System Oscillation Technique

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    A flight flutter testing technique is described in which the rotor controls are oscillated by series actuators to excite the rotor and airframe modes of interest, which are then allowed to decay. The moving block technique is then used to determine the damped frequency and damping variation with rotor speed. The method proved useful for tracking the stability of relatively well damped modes. The results of recently completed flight tests of an experimental soft-in-plane rotor are used to illustrate the technique. Included is a discussion of the application of this technique to investigation of the propeller whirl flutter stability characteristics of the NASA/Army XV-15 VTOL tilt rotor research aircraft
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